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KMID : 0964020120120010067
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Journal of the Korean Liver Cancer Study Group
2012 Volume.12 No. 1 p.67 ~ p.70
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A Case of Successful Treatment of Hepatocellular Carcinoma with a Pulmonary Metastasis by Combining Pulmonary Wedge Resection and Sorafenib
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Lee Sun-Jae
Yim Hyung-Joon
Chung Hwan-Hoon
Kim Hae-Rim
Yoon Eileen L.
Hyun Jong-Jin
Jung Sung-Woo
Koo Ja-Seol
Choung Rok-Seon
Lee Sang-Woo
Choi Jai-Hyun
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Abstract
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35-year-old female patient was diagnosed with hepatocellular carcinoma and underwent hepatic resection. 12 months after
hepatic resection, serum AFP rose (119.6 ng/mL) but no definite recurrence was found on imaging modalities. 30 months after hepatic resection, serum AFP rose up to 1008.5 ng/mL and metastatic nodule was found in right lower lung in chest CT. Video assisted thoracoscopic wedge resection was performed and 400 mg/day of sorafenib was intiated. Serum AFP returned to normal range after 2 months of pulmonary resection. No evidence of recurrence is noted after 30 months of pulmonary resection. We think that pulmonary resection plus sorafenib combination therapy resulted in favorable treatment outcome in this patient.
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KEYWORD
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Hepatocellular carcinoma, Pulmonary resection, Sorafenib
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